Vulvodynia is a chronic vulvar painful disease that may involve a burning or itchy feeling. The illness is frequently caused by neurological discomfort rather than an infection or an acute injury. Treatment for vulvar pain is a staple of dermatological treatment, with several advantages such as ease of use, a lack of systemic adverse effects, and patient-directed application.
According to studies, using a topically applied cream can considerably decrease discomfort from this disease. Vulvodynia can cause significant discomfort and affect a woman’s ability to do everyday tasks, thus effective long-term treatment is important. Certain friction-producing activities, such as riding or sitting, may worsen the pain. Pain is significantly less noticeable while lying down. Pudendal, ilioinguinal, or genitofemoral neuralgia is a common cause of vulvar discomfort for which there is no alternative explanation.
This cream for vulvar pain applied directly to the vulva can help relieve discomfort, certain formulations contain addictive ingredients that are unpleasant to the skin. As a result, many vulvodynia specialists turn to compounding pharmacies to create customized topical lotions and ointments free of irritating chemicals.
Here are several examples:
- Topical Hormonal Creams (e.g: Syren intimate Relief): Topical cream can enhance the condition of vulvar tissue, especially if it is weak or dry due to a lack of estrogen. Some doctors have recently emphasised the function of the hormone testosterone in women’s sexual health and advocate mixing oestrogen and testosterone in a topical cream.
- Topical Anesthetics (e.g., lidocaine): Before intercourse, a topical anesthetic cream or ointment is applied directly to the vulva to give temporary pain relief. The numbing effect lasts from 15 to 30 minutes. According to one study, long-term nighttime lidocaine usage resulted in long-term pain alleviation.
- Topical Compounded Formulations: Antidepressants and anticonvulsants, which are often taken orally, can also be made as a cream or ointment. Topical treatments for vulvodynia may contain a single active ingredient or a combination of active ingredients, such as an anesthetic and an antidepressant. Compounded topical formulations can be used in conjunction with oral medications and other treatments.
Chronic Pain and Nerve Damage
Vulvodynia symptoms can be caused by an injury to the genitofemoral, ilioinguinal, or pudendal nerves, or a combination of these. The most common cause is a groin injury after surgery, however the reason is usually unclear. A biopsy cannot identify the illness, and it is not caused by an infection or inflammation. While neuropathic vulvar discomfort is widespread, it is less likely to be recognised since no apparent changes occur. Because this illness is not well-known among doctors, alternative medications that are ineffective for this sort of pain are occasionally used.
The quality of life of a woman can be significantly impacted by vulvar neuropathic pain. Women suffering with vulvodynia may experience depression in addition to the symptoms of the disorder. Pain symptoms include burning, itching, soreness, and rawness. This pain may make it difficult for a woman to engage in sexual activity, exercise, employment, or other physical activities. Sitting for long periods of time may worsen vulvar pain.
Nerve blocks and surgical procedures have been used to treat vulvodynia, with some causing serious harm. The most commonly used treatments are drugs such as antidepressants and anticonvulsants such as orally administered anticonvulsants. As vulvodynia is a chronic condition, therapy should typically be ongoing. Many women choose a treatment with less systemic side effects, such as gabapentin topical cream. For menopausal women, an oestrogen cream may also be an effective long-term treatment.
Gabapentin for Neuropathic Pain Treatment
Gabapentin is an anticonvulsant medication that was licensed in 1993 and is marketed under the trade name Neurontin. It became released as a generic in 2004 and has subsequently been prescribed for a range of purposes. It does not cure epilepsy, but when used consistently, it can help to manage symptoms. It can also be used orally to treat neuropathic pain.
Many off-label uses of Gabapentin have been demonstrated to be helpful in limited trials, including treatment for diabetic neuropathy and postherpetic neuralgia.
Gabapentin acts to treat vulvodynia by blocking pain signals delivered by damaged neurons. According to a retrospective research published in Obstetrics and Gynecology showed that gabapentin cream was well tolerated and beneficial for women with vulvodynia.
Approximately 80% of the ladies who used the cream reported at least a 50% improvement in pain levels. The women’s sexual functioning improved as well, and the majority resumed vaginal intercourse following therapy.
The vulva is a very prevalent site of chronic pain with neuropathic features in women of all ages, yet most women with neuropathic type chronic vulvar pain go misdiagnosed despite many medical visits. Chronic “unexplained” vulvar pain, described as searing or sharp knife-like pain or pain on touching, was identified in the largest community-based study ever conducted. It lasts at least 3 months or more, according to nearly 7% of women aged 18–64 in a US urban region.
Despite this high frequency, the latter research indicated that a majority of women suffering with persistent vulvar discomfort had no accurate diagnosis, even after several physician visits,2 a finding that has been verified by other recent US population-based investigations.
The clinical responses of topical gabapentin were determined by a prospective study.Patients’ demographic and medical information, including current and former vulvodynia treatment, were routinely obtained. The ultimate outcome was determined by comparing pretreatment and posttreatment mean pain levels on a 0 to 10 discrete visual analogue scale. The Fisher exact test was used to compare categorical data, the Wilcoxon rank sum test was used to compare continuous variables between groups, and the paired Student test was used to evaluate the mean change in pain score between pretreatment and posttreatment.
According to the International Society for the Study of Vulvovaginal Disease, vulvar pain can be generally categorized as pain connected to a specific condition, either as pain occurring in the absence of relevant visual symptoms or a specific clinically recognisable, neurologic disease.
Vulvar pain produced by a particular illness comprises pain caused by infectious disease (for example, herpes genitalis), inflammatory mucocutaneous disease (for example, lichen planus), neoplastic disease (for example, squamous cell carcinoma), and neurological disease (for example, postherpetic neuralgia)..
If no such underlying condition to vulvar suffering can be found, the word vulvodynia has been accepted, etymologically referring to vulvar pain. Vulvodynia is characterized in the majority of the patients by mechanical allodynia and hyperalgesia of the vaginal vestibular area, which is thought to be associated, at least in part, to significant regional C-fiber hyperinnervation and perhaps neuroinflammation.
While the nosology of vulvodynia has long been debated, the signs and symptoms of vulvodynia significantly coincide with neuropathic pain, as determined by existing screening techniques.
51 women with vulvodynia were treated with 2% to 6% gabapentin between January 2001 and December 2006.. The mean pain score among the 35 evaluable women significantly decreased from 7.26 to 2.49 after a minimum of 8 weeks of treatment (mean change –4.77, 95 percent confidence interval –5.47 to –4.07). In all, 28 of the 35 individuals’ pain scores improved by at least 50%. (80 percent ).
Sexual function improved in 17 of the 20 individuals with localised vulvodynia who had evaluable findings (6 of 9 reinstituted vaginal intercourse, whereas all 11 patients experiencing decreased frequency of intercourse reported increased frequency after treatment). Discontinuations occurred in 7 of the 50 patients (14 percent).
In women with vulvodynia, topical gabapentin appears to be well tolerated and linked with considerable pain alleviation. In women with vulvodynia, topical gabapentin cream enhanced sexual function.
Benefits Of Using Syren Intimate Relief
- Some vulvodynia symptoms can be relieved by using Syren topically.
- Syren is used to prevent thin and dry vaginal tissue, and it can also aid with external genitals.
- The use of Syren cream can increase tissue thickness and alleviate some of the discomfort associated with the effects of decreased hormone production during menopause.
- There may be a minor sting upon application, but it is short.
- You can use it as often as you like and there will be no bad consequences.
- Forget about greasy creams and ointments. Syren Intimate Relief is much easier to apply and distributes evenly on the skin. You’ll forget you ever used it after it’s been absorbed!
- Apply the gel to your vulva as needed. No more waiting and experiencing agony till the appropriate moment for application. It has no odor and will not stain your undergarments.
The vulva is the external female genital region.This type of pain is really prevalent. Vulvodynia is pain that lasts three months or more and is not caused by an infection, skin disease, or other medical issue. Vulvodynia symptoms include burning, stinging, inflammation, and rawness. The entire vulva may be uncomfortable, or the discomfort may be concentrated in one place. Symptoms may appear and disappear without notice, or they may appear only when the affected region is handled. As a result, this vulvar pain treatment works wonders for the ladies who are affected by it.